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Microbiology General 891ddbe3

The endotoxin of the following gram negative bacteria does not play any pa in the pathogenesis of the natural disease.

A
E. coli
B
E. coli
C
Vibrio cholerae
D
Pseudomonas
High-Yield Explanation
Ans. is 'c' i.e., Vibrio cholerae . Cholera vibrios possess the lipopolysaccharide 0 antigen (LPS endotoxin), but it has no role in pathogenesis. About other options . Somatic lipopolysaccharide surface 0 antigen of E.coli has endotoxic activity and also protect the bacilli from phagocytosis . Long chain lipopolysaccharide (endotoxin) of klebsiella protects it from the action of serum complement . Endotoxin of pseudomonas causes fever, leukocytosis or leukopenia, shock, DIC, hypotension, ARDS, SIRS.

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