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Surgery Plastic Surgery and Skin Lesions 88fa0e62

The following statement about this condition is true:

A
Elevated levels of growth factor is not seen
B
Extended excision is the treatment of choice
C
It do not extend beyond the wound
D
It will have more collagen and vascularity
High-Yield Explanation
The given condition is keloid. Keloid- Has Excessive scar tissue- Scar extends beyond the boundaries of original wound or incision - Etiology - Unknown- Associated with* Elevated levels of growth factors* Deeply pigmented skin* Genetic predisposition* Areas of body where there is increased risk of keloid formation- Above clavicle- Upper extremities- Trunk & Face- Especially seen in the Triangular region with boundaries of Each shouldertip and Xiphisternum - On Histology* Excess collagen & Hypervascularity* Contains disorganized Type I & III collagen* Contains thicker collagen bundles - causes formation of acellular node like structures* Rarely regresses with time* Often refractory to Medical & Surgical intervention - Treatment* First line treatment - Silicones + Pressure therapy + Intralesional injection of triamcinolone * In Refractory Cases (No improvement after 12 months of treatment) - Excision + Post-operative Radiotherapy (External beam radiotherapy / Brachytherapy)

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