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Medicine Kidney 88989500

All are features of renal tubular acidosis type I except-

A
Stone in kidney
B
No anion gap
C
Hypokalemia
D
Fanconi syndrome
High-Yield Explanation
Type1A-classical distal A include- hypoklaemia non-anion gap metabolic acidosis , low urine ammonium excretion, high urine PH. Most of them also have hypocitrauria, hypercalciuria, so nephrolithiasis nephrocalcinosis and bone disease are common. Type2A-proximal A( FANCONI SYNDROME) -generalized proximal tubular dysfunction resulting in Glycosuria Phosphaturia Generalized aminoaciduria Type3A-rare Type4A-generalized distal A Hyperkalemia Decreased ammonia excretion . Many patients have hyporeninemic hypoaldosteronism causing non anionic gap metabolic acidosis . Ref:HARRISON 20th edition pg no. 320

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