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Medicine viral infection 884ef862

Rapid diagnosis of rabies is made with?

A
Skin biopsy with fluorescent antibody testing
B
Rabies virus specific antibodies
C
Inoculation in mouse
D
Corneal impression smear
High-Yield Explanation
Biopsy is taken from nape of neck, rabies virus present in hair follicle. Rabies-Lab Diagnosis Rabies Antigens or Nucleic Acids detection: Immunofluorescence or immunoperoxidase staining Biopsy specimen from skin of the neck at hairline Impression preparations of brain or cornea tissue Negri bodies in the brain-80% positivity -PCR test on brain tissue specimen Viral Isolation Tissue is inoculated intra-cerebrally into suckling mice Serology Serum / CSF anti-rabies Ab by immunofluorescence Animal observation

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