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Biochemistry Respiratory chain 8847bbfa

MELAS is an inherited condition which occurs due to deficiency of

A
Complex I
B
Complex II
C
Complex III
D
All the above
High-Yield Explanation
MELAS (mitochondrial encephalopathy, lactic acidosis, and stroke) is an inherited condition due to NADH-Q oxidoreductase (Complex I) or cytochrome oxidase (Complex IV) deficiency. It is caused by a mutation in mitochondrial DNA and may be involved in Alzheimer disease and diabetes mellitus. Reference: Harper; 30th edition; Page no: 135

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