Full 2L QBank
Biochemistry Metabolism of protein and amino acid 8824d768

In Kreb's cycle and Urea cycle the linking component is

A
Arginine
B
Aspaate
C
Ammonia
D
Fumarate
High-Yield Explanation
Urea cycle * Cleavage of argininosuccinate by argininosuccinate lyase, results in formation of arginine and release of the aspaate skeleton as fumarate (funnelled into TCA cycle) * Subsequent addition of water to fumarate forms l-malate, with subsequent oxidation forms oxaloacetate, followed by its transamination by glutamate aminotransferase then re-forms aspaate. * Argininosuccinate synthase links aspaate and citrulline forms argininosuccinate. * Thus the urea cycle is linked to TCA cycle through fumarate Ref:- Harper 30/e; pg num:- 294

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