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Physiology All India exam 87a2c321

which statemenr is false regarding ascending limb of loop of henle?

A
its highly permeable to sodium
B
channel is Na+K+ 2cl- defect leads to pendred syndrome
C
its permeable to magnesium
D
its a pa of counter current multiplier
High-Yield Explanation
COUNTER CURRENT MECHANISM IN KIDNEY * long loop of Henle establishes a veical osmotic gradient (Countercurrent multiplier) their vasa recta preserve this gradient while providing blood to renal medulla Countercurrent exchanger) collecting ducts of all nephrons use the gradient in conjunction with the hormone vassopressin, to produce urine of varying concentration (osmotic equilibrating device) Collectively this entire functional organization is known as medullary countercurrent system. ascending limb of loop of henle is permeable to sodium,potassium , chloride and magnesium its a pa of CCM- dilution segment defect of na+k+2cl- is called baer syndrome ref: guyton and hall

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