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Pediatrics Hematology 878c57c1

Ba&;s hydrops fetalis is lethal because

A
Hb Ba's cannot bind oxygen
B
The excess a - globin form insoluble precipitates
C
Hb Ba's cannot release oxygen to fetal tissues
D
Microcytic red cells become trapped in the placental
High-Yield Explanation
Ba hydrops fetalis is a lethal complication of alpha thalassemia trait where oxygen can&;t release from hemoglobin. Hb Bas is formed of 4 gamma chains. The oxygen affinity is so high that it releases very little oxygen into the fetal tissues. Reference: Ghai essential of pediatrics, eighth edition, p.no:342

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