A 16 years old girl came for evaluation of primary amenorrhea. She was having hirsutism, irregular bleeding and infeility, diagnosed as PCOS. Which of the following drugs should not be given?
High-Yield Explanation
Answer- B. TamoxifenMedical Treatment of PCOSEstrogen best given with progesterone (combined OCPs) with no androgenic propeiesHirsutism is treated with cyproterone acetate or spironolactone.Infeility is treated with Clomiphene, 80% ovulate and 40% conceive.In Clomiphene failed group, ovulation can be induced with FSH or GnRH analogues.Metformin treats the root cause of PCOS, rectifies endocrine and metabolic functions and improves feility and isdrug of choice.