The pulseless disease is -

Takayasu arteritis Takayasu arteritis is granulomatous vasculitis of large and medium arteries. It is characterized principally by ocular disturbance and marked weakening of pulses in the upper extremities Pulseless disease. It is also characterized by a strong predilection for aortic arch and its branches → Aortic arch syndrome. It is more common in Adolescent girls and young women. Morphological changes in vessel wall are same as in giant cell arteritis. Clinical presentation Symptoms are mainly according to the involved vessel - C Subclavian artery : Most commonly involved vessel Symptoms are - Arm claudication, lower BP and weaker pulse in upper limb than in lower limb, Raynaud's phenomenon. Common carotid → Visual disturbances, stroke, TIA, syncope. Abdominal aorta or coeliac artery or superior mesenteric artery → Abdominal pain, nausea, vomiting Renal → Hypertension, Renal failure Aortic root  → Aortic regurgitation, CHF Vertebral → Visual disturbances Iliac → Leg claudication Pulmonary → Pulmonary hypertension, dysnea, chest pain. Coronary → Angina, MI Constitutional symptoms → As with other vasculitis malaise, fatigue, anorexia and weight loss are common. Elevated ESR and Anemia (as with other vasculitis)