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Microbiology Virology 872d1ff7

HPV causes which change in cervical epithelium

A
Induction of apoptosis
B
Induction of necrosis
C
Immortalization of epithelial cells
D
By stimulating telomerase
High-Yield Explanation
Ans. is 'c' i.e., Immortalization of epithelial cells o HPV selectively infects the epithelium of skin and mucous membrane and may immortalize the keratinocytes leading either asymptomatic infection, or warts or neoplasia.o Products of E-genes (E6, E7) are related to immortalization or malignant transformation of keratinocytes by interfering with p53 and Rb genes, respectively.

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