Surgery Trauma 8708fbd5

All of the following are true about CRASH-2 trial except:

Dose of tranexamic acid is 1 gm IV over 10 minutes followed by 1 gm over 8 hours

Given to all trauma patients suspected to have significant hemorrhage including SBP <110 mm Hg or PR >110/min

Should be administered within 3 hours of injury

Tranexamic acid reduces the risk of moality from bleeding in blunt trauma but not in penetrating trauma

High-Yield Explanation

CRASH-2 TRIAL* Recommends use of Tranexamic acid in hypotensive trauma patients* 1 gm I/V over 10 minutes followed by 1 gm over 8 hours* Advantages- Reduces the risk of moality from bleeding in both blunt & penetrating trauma* Indications for Tranexamic acid- All trauma patients suspected to have significant hemorrhage including SBP < 110 mmHg or PR > 110/min- Administrated within 3 hours of injury

All of the following are true about CRASH-2 trial except:

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