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Pharmacology General 86a598a6

Linaclotide is a

A
Chloride channel activator
B
CFTR blocker
C
Somatostatin antagonist
D
Guanylate cyclase agonist
High-Yield Explanation
Linaclotide is a Guanylate cyclase - C agonist that increases levels of cGMP and stimulates secretion of chloride & bicarbonate ions into the intestinal lumen. It is used in treatment of IBS with constipation.

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