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Medicine Leukemia 869d302b

Which one of the following laboratory test differentiates leukamoid reaction from chronic myeloid leukemia?

A
LAP (leukocyte alkaline phosphatase)
B
LCA (leukocyte common antigen)
C
MPO (myelo-peroxidase)
D
TRPA (tartrate resistant alkaline phosphatas
High-Yield Explanation
Ans. is 'a' i.e., LAP (leukocyte alkaline phosphatase) o A leukemoid reaction is an exuberant form of ieucocytosiswith leucocyte count upto 50000/mm3, that may follow infections.It is difficult to distinguish leukemoid reaction from leukemia.Absence of Philadelphia chromosome and increase in leucocyte alkaline phosphatase score rules out CML. CMLLeukemoidpH chromosome+ve-veALPDecreasedIncreased

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