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Biochemistry HAEM synth and porphyrias 86986345

All of the following will cause a shift to the right of the oxygen-hemoglobin dissociation curve, EXCEPT

A
Hypoxia
B
2,3 DPG
C
Increase in pH
D
Increase in temperature
High-Yield Explanation
In oxygen dissociation curve (ODC) of Hb, paial pressure of oxygen is plotted on the X-axis and percentage of hemoglobin saturated with oxygen is plotted on the Y-axis. We get a sigmoidal curve for hemoglobin. Shift of oxygen dissociation curve to right refers to the increased unloading of oxygen. Imagine a person doing exercise in a warm room. Raised CO2, temperature, 2,3-DPG and decreased pH causes shift of ODC to right.

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