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Pharmacology Kidney 86954524

All of the following statements about amiloride are true EXCEPT:

A
It antagonises the action of aldosterone
B
It is the drug of choice for the treatment of lithium induced diabetes insipidus
C
It decreases calcium loss in the urine
D
It is more potent than triamterene
High-Yield Explanation
Amiloride acts by blocking epithelial Na+ channels. It has no effect on aldosterone receptors. It is more potent than triamterene. It decreases Ca2+ loss in the urine It is the drug of choice for lithium induced DIas it blocks entry of Li ions through ENac channels.
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