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Pharmacology All India exam 86798aef

Many signaling pathways involve the generation of inositol trisphosphate (IP3) and diacylglycerol (DAG). These molecules

A
Are first messengers
B
Activate phospholipase C
C
Are derived from PIP2
D
Can't activate calcium calmodulin-dependent protein kinases directly or indirectly
High-Yield Explanation
IP3 DAG are secondary messengers derived from PIP2 they are present in the cell membrane where IP2 crosses the cell membrane and DAG doesnot. Ref: KD Tripathi 8th ed.

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