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Orthopaedics Metabolic Disorders Leading to Osteosclerosis 85f546c3

Which of the below is a feature of Osteogenesis imperfecta?

A
Blue sclera
B
Cataract
C
Anterior uveitis
D
Retinal detachment
High-Yield Explanation
Ans. is 'a' i.e., Blue sclera o Osteogenesis imperfecta, also known as brittle bone disease, is due to defective collagen type 1 synthesis.o It is inherited mostly as autosomal dominant but autosomal recessive pattern also seen in severe form. Clinical features of osteogenesis imperfecta# Blue sclera# Dentinogenesis imperfecta a Generalized osteoporosis# Osteoporosis given rise to bowing and multiple fractures. Fracture are usually due to trivial trauma but surprisingly heal well.# Other features: Deafness due to otosclerosis, joint laxity, dwarfism, broad skull, poorly calcified decidual teeth (Permanent teeth are normal).# Radiology shows wormian bones in the skull.

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