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Biochemistry General 85f3b0e9

A 28 year old man complains of abdominal bloating and diarrhoea following a meal with paneer, a dairy product. These symptoms are absent with other foods. Which of the following enzyme is likely deficient in this patient?

A
a-amylase
B
3-galactosidase
C
a-glucosidase
D
Sucrase
High-Yield Explanation
This patient is showing the symptoms of disaccharide intolerance (Lactose, Sucrose, Maltose). Most likely it is lactase deficiency. But it is not given in the options. So the answer goes to Sucrase. A disaccharide intolerance is a manifestation of carbohydrate malabsorption. In most people, lactase is gradually lost through adolescence, leading to lactose intolerance. Ref: Harper's Biochemistry, 26th Edition, Page 475 ; Wheat-Free, Worry-Free By Danna Korn, 2002

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