A patient with acute history of blistering and denudation involving >30% BSA along with erosions of the lips with hemorrhagic crusting and other mucosa for few days. What is the most common triggering factor?
High-Yield Explanation
Lesions >30% BSA , erosion over lips and mucosa : Dx TEN TEN SJS: Haemorrhagic Crusting Sloughing of mucosa Targetoid lesion (2 rings) Nikolsky sign (Pseudo) due to epidermal necrosis. Epidermal necrosis (SJS/TEN) Etiology: Drugs: -Antiepileptic( MC) - CBZ, Lamotrigine * NSAIDS * Penicillin * Nevirapine CBZ induced SJS/TEN is a/w HLA B1502