All of the following statements are true regarding ondansetron except:-
High-Yield Explanation
ONDANSETRON Main mechanism of action of ondansetron is 5HT3 antagonism. It has minor 5HT 4 agonist action which is clinically insignificant. It does not block dopaminergic receptors. It is drug of choice for chemotherapy induced vomiting, radiation induced vomiting and post-operative vomiting. No clinically significant drug interactions have been noted with ondansetron