Gynaecology & Obstetrics Normal Menstruation, Abnormal Menstruation, Menopausal Physiology and forsight of conception 8546c481

Which out of these is the cause of menopause?

Ovarian failure secondary to cessation of pituitary secretion of gonadotropins

Ovarian failure secondary to cessation of hypothalamic secretion of GnRH

Deranged hypothalamic-pituitary-ovarian axis functioning

Primary ovarian failure

High-Yield Explanation

Menopause occurs due to Ovarian failure which occurs due to programmed apoptosis of ovarian follicles. Please note : The HPO axis remains intact even in older women and because of the integrity of this axis, there is an increase in FSH due to loss of inhibitory feedback of estrogens on pituitary.

Which out of these is the cause of menopause?

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