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Surgery FMGE 2018 84dad694

All of the following are features of Zollinger-Ellison syndrome except:-

A
Intractable peptic ulcers
B
Severe diarrhea
C
Arise from beta cell tumors of pancreas
D
Very high acid output
High-Yield Explanation
ZESaAKA Gastrinoma - arise from G- cells/ Gastrin producing cells Has increased gastrin production causing increased acid production- leads to peptic ulcer disease Causes of diarrhea: -Acid produced reaches duodenum and inactivate pancreatic enzymes(works only in alkaline ph) causing Malabsorption -Acid reaches proximal jejunum and causes irritation- leads to jejunal secretion

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