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Pathology Blood Vessels 84c43f33

In atherosclerosis, increased LDL in monocyte macrophage due to:

A
LDL receptors on macrophage
B
LDL receptors on endothelium
C
Lipids in LDL get oxidized
D
All of the above
High-Yield Explanation
Ans. (c) Lipids in LDL get oxidized(Ref: Robbins 9th/pg 496; 8th/pg 500)With chronic hyperlipidemia, lipoproteins accumulate within the intima, there they aggregate and become oxidized by free radicals produced by inflammatory cells.

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