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Physiology Cell Physiology and Intercellular Connections 847d60c6

All of the following enzymes are active within a cell except:

A
Trypsin
B
Fumerase
C
Hexokinase
D
Alcohol dehydrogenase
High-Yield Explanation
Ans. is 'a' ie Trypsin (Ref: Guyton and Hall, 10/e, p746; Harper's Biochem, 26/e, p76).Trypsin is a powerful pancreatic proteolytic enzyme which would digest the pancreatic cell that produced it, if not have been produce as a proenzyme (- its inactive form known as trypsinogen.) Trypsinogen is activated in the intestinal tract by enzyme called enterokinase.Pancreas has additional protective mechanism against self digestion by Trypsin - Secretion of trypsin inhibiter.All other options are enzymes of the glycolytic pathway which are in their active form within the cells.

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