18-year-old girl with primary amenorrhea having a karyotype of 45X0 presents with infantile uterus. What should be done next?

ANS. AThe primary treatments for all girls and women with Turner's syndrome include hormone therapies (growth hormone and estrogen).It is important to identify a Y chromosome because affected individuals are at a risk of gonadoblastoma (20 to 30%). Only in such cases we need to do gonadectomy.Hence, the answer for this question is HRT to induce Puberty.Evaluation of primary amenorrheaSecondary sexual characters|| |Normal* MRKH* AIS* Transverse vaginal septum* Imperforate hymen Absent* Turner's syndrome* Kallman syndrome* Swyer's syndromeAbbreviation: MRKH, Mayer-Rokitansky-Kuster-Hauser; AIS, Androgen insensitivity syndrome