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Pharmacology General 845f4a28

Which of the following chemotherapeutic drugs has selective action on hypoxic tumor cells ?

A
Mitomycin C
B
Cisplatin
C
Doxorubicin
D
5 Flurouracil
High-Yield Explanation
Ans. is 'a' i.e., Mitomycin Some impoant points about mitomycin. Mitomycin acts preferrentially on hypoxic cells It is a potent radiosensitizer It is absorbed consistently from Gl. tract so it administered by intravenous infusion

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