Tranylcyprominle (MAO Inhibitor) should be avoided with ............... as it causes dangerous drug interaction:
High-Yield Explanation
MAO inhibitor with tricyclcic anti depressants (amitriptyline), reserpine , guanethidine can cause excitement , rise in BP and body temperature. This is due to their initial NA releasing it uptake blocking action. MAO inhibitor also interacts with cold and cough remedies that contain sympathetomimetic , levodopa , barbiturates, alcohol, opiod and antihistamine and antiparkinsonian anticholinergic . REF: KD Tripati 8th edition