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Pharmacology FMGE 2017 84155350

Mechanism of action of Pemetrexed is:-

A
RNA synthesis inhibitor
B
Dihydrofolate reductase inhibitor
C
Dopamine agonist
D
Topoisomerase inhibitor
High-Yield Explanation
Dihydrofolate reductase Inhibitors Methotrexate Pralatrexate Pemetrexed PEMETREXED - used in mesothelioma D: Topoisomerase introduces negative coil's and aids in replication IRINOTECAN - topoisomerase Inhibitor

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