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Pathology General 840ad4b5

Diffuse multiple bone involvement, cafe-au-lait pigmentation and endocrine disturbances are the features of:

A
McCune Albright syndrome
B
Jaffe's syndrome.
C
Mazabrauds syndrome
D
All of the above
High-Yield Explanation
Polyostotic Fibrous dysplasia is of 2 types. In Jaffe type there is multiple bone involvement associated with cafe-au-lait spots. Extreme or diffuse multiple bone involvement, cafe-au-lait pigmentation, and endocrine disturbances are important features of McCune-Albright's syndrome. In polyostotic form, the curvature of femoral neck and proximal shaft of the femur increase markedly causing a shepherd's crook deformity.

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