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Pathology General 84042eae

Which gene is mutated in Cowden syndrome?

A
SMAD 2
B
PTCH
C
PTEN
D
APC
High-Yield Explanation
Cowden syndrome is also known as multiple hamartoma - neoplasia syndrome. It is due to PTEN gene mutation. It increases the risk of Ca Breast, Ca endometrium and thyroid cancers.

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