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Microbiology Gram-Positive Infections - Corynebacterial Infections 83e715f1

What is the sequence which a retrovirus follows on entering a host cell?

A
RNA - DNA - RNA
B
RNA - DNA
C
DNA - RNA
D
DNA - RNA - DNA
High-Yield Explanation
Ans. is 'a' i.e., RNA - DNA - RNA(Ref: Ananthanarayan, 9th/e, p. 574 and 8th/e, p. 570)* When HIV infects a cell, the viral RNA is transcribed by reverse transcriptase, first into single stranded DNA and then to double stranded DNA (Provirus).* Provirus is integrated into host cell chromosome.* This provirus initiates viral replication by directing synthesis of viral RNA, in response to viral promoters.

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