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Pathology General 83a28706

The following element is an impoant constituent in Paneth cells:

A
Zinc
B
Copper
C
Molybdenum
D
Selenium
High-Yield Explanation
Paneth cells, located in the basal poion of the intestinal crypts below the stem cells, are exocrine cells with large, eosinophilic secretory granules in their apical cytoplasm. Paneth cell granules undergo exocytosis to release lysozyme, phospholipase A2, and hydrophobic peptides called defensins, all of which bind and breakdown membranes of microorganisms and bacterial walls. Paneth cells have an impoant role in innate immunity and in regulating the microenvironment of the intestinal crypts. They also contain Zinc. Ref: Paulsen D.F. (2010). Chapter 15. Digestive Tract. In D.F. Paulsen (Ed), Histology & Cell Biology: Examination & Board Review, 5e.

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