An 18 years old girl presents with primary amenorrhea. On evaluation, she was having a karyotype of 45X0 and infantile uterus. What should he done next?

Ans. d. Bilateral gonadectomyHistory of primary amenorrhea, karyotype of 45X0 & infantile uterus is suggestive of Turner's syndrome. Approximately 5% of women with Turner's syndrome have a karyotype with Y chromosome (45X/46XY). It is impoant to identify' a Y chromosome because affected individuals are at significant risk of gonadoblastoma (20 to 30%). Therefore, prophylactic gonadectomy should be performed.