A 24 week pregnant female developed gestational diabetes. Which of the following is the MOST characteristic congenital anomaly of diabetic pregnancy?
High-Yield Explanation
The commonest congenital anomalies seen in infants of diabetic mothers are cardiac anomalies, neural tube defects, and genitourinary abnormalities. Caudal regression is most characteristic. Other congenital malformations: Anencephaly Spina bifida, hydrocephalus, or other central nervous system defects Cardiac anomalies Transposition of great vessels Ventricular septal defect Atrial septal defect Anal/rectal atresia Renal anomalies Agenesis Cystic kidney Ureter duplex Situs inversus Ref: German M.S. (2011). Chapter 17. Pancreatic Hormones and Diabetes Mellitus. In D.G. Gardner, D. Shoback (Eds), Greenspan's Basic & Clinical Endocrinology, 9e.