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Pathology General 837386f8

Nitric oxide is synthesised from:

A
Cysteine
B
Cystine
C
Methionine
D
Arginine
High-Yield Explanation
NO is synthesized from l-arginine by the enzyme nitric oxide synthase (NOS). There are three different types of NOS: endothelial (eNOS), neuronal (nNOS), and inducible (iNOS). eNOS and nNOS are constitutively expressed at low levels and can be activated rapidly by an increase in cytoplasmic Ca2+. iNOS, in contrast, is induced when macrophages and other cells are activated by cytokines (e.g., TNF, IFN-g) or microbial products. Ref: Robbins 8th edition, Chapter 2.

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