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Pharmacology General 8320d1e0

Centrilobular zonal necrosis in liver is seen with which of the following drug?

A
Carbon tetrachloride
B
Rifampicin
C
INH
D
Yellow phosphorus poisoning
High-Yield Explanation
Carbon tetrachloride characteristically produce a centrilobular zonal necrosis, whereas yellow phosphorus poisoning typically results in peripoal injury. Ref: Harrisons Principles of Internal Medicine, 18th Edition, Page 2558.

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