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Pharmacology Chemotherapy: General Principles 82269d64

Mechanism of action of protease inhibitors is:

A
Prevents maturation of new viral particles
B
Prevents translation of viral RNA
C
Causes apoptosis of the affected cells
D
Inhibits proviral RNA synthesis
High-Yield Explanation
Ans. (A) Prevents maturation of new viral particles(Ref: KDT 7/e p809)Function of protease enzyme in HIV is to break inactive polyproteins to functional components. This post-translational modification is required for maturation of new viral particles. Protease inhibitors like atazanavir inhibit this step.

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