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Pharmacology C.V.S 81707dd0

You decide not to give sildenafil to patient who is on antianginal drug, which of the following drug it can be?

A
Calcium channel blockers
B
Beta blockers
C
Nitrates
D
ACE inhibitors
High-Yield Explanation
Ans. C. NitratesNitrates act by increase CGMP and sildenafil decrease the breakdown of this compound. Marked increase in CGMP results in profound hypotension and reflex tachycardia.

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