Trans-placental spread is least associated with ?

HSV infection may be acquired in utero, during the bih process,or during the neonatal period. Intrauterine and postpaum infections occur infrequently. Most cases of neonatal herpes result from maternal infection and transmission usually during passage through a contaminated infected bih canal of a mother with asymptomatic genital herpes. TRANSPLACENTAL spread is associated with the following - Toxoplasmosis,syphilis, parvovirus,rubella, cytomegalovirus (TORCH)infections. some other bacterial infections also occur transplacentally like TREPONEMA pallidum, LISTERIA monocytogenes. Reference: Nelson textbook of pediatrics 19th edition Page 1101