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Pharmacology Hypeension, Arrhythmias, Dyslipidemia 80ffd17b

Which of the following drugs when combined with erythromycin may cause ventricular arrhythmias?

A
Tetracycline
B
Streptomycin
C
Ebastine
D
Cisapride
High-Yield Explanation
As Erythromycin is enzyme inhibitor of CYP3A4 --> concentration of drugs like cisapride, Terfenadine and Astemizole increases--> blocking the K+ channel --> QT prolongation --> ventricular arrhythmias.

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