Tophi in gout found in all regions except -a) Joint capsuleb) Skinc) Muscled) Articular cartilagee) Synovial membrane
High-Yield Explanation
Tophi are pathognomic of gout. They are formed by large aggregations of urate crystals. The urate crystals are surrounded by -
Macrophages
Lymphocytes
Large foreign body giant cells
They are seen in the-
Articular cartilages of joints
Periarticular ligaments
Tendons and soft tissues
Achilles tendon
Ear lobes
Less common sites of involvement are -
a) Kidney
b) Nasal cartilage
c) Skin of the finger tips, palms or soles.