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Microbiology General 80859c3e

A patient was brought to emergency with complaints of high-grade fever and altered sensorium. He was diagnosed to be suffering from meningococcal meningitis. Which of the following is the most appropriate empirical treatment option?

A
Ceftriaxone
B
Piperacillin--Tazobactam
C
Penicillin
D
Cotrimoxazole
High-Yield Explanation
Answer- A. CeftriaxoneMeningococcal meningitisTreatment:3rd generation cephalosporin such as cefotaxime or ceftriaxone is DOC for initial therapyProphylaxis: Rifampicin is DOC for meningococcal prophylaxisANTIBIOTIC RECOMMENDATIONS FOR BACTERIAL MENINGITIS:BACTERIAANTIBIOTIC(IV)DURATIONStreptococcus PneumoniaVancomycin+3rd gen. Cephalosporin(Cefotaxime or ceftriaxone) 10-14 daysNesseria meningitidis3rd gen. Cephalosporin(Cefotaxime or ceftriaxone) orPenicillin G or Ampicillin 5-10 days H.influenza3rd gen. Cephalosporin(Cefotaxime or ceftriaxone) 7-10 days Listeria monocytogensPenicillin G or Ampicillin + Aminoglycocide14-21 days GBSPenicillin G or Ampicillin + Aminoglycocide 14-21 days E.coli 3rd gen. Cephalosporin(Cefotaxime or ceftriaxone) 21 days

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