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Gynaecology & Obstetrics Carcinoma Ovary 808487cb

The following statements are related to Krukenberg tumor except:

A
It is always secondary
B
The most common primary site is pylorus of the stomach
C
The tumor is bilateral
D
'Signet ring' looking cells are characteristic
High-Yield Explanation
Ans. is a, i.e. It is always secondaryRef: Dutta Gynae 6th/ed, p387* Krukenberg tumor is generally a metastatic tumor to the ovary. But "Krukenberg tumor may be a primary tumor" - Ref: Dutta Gynae 6th/ed, p387* The most common primary sites from where metastases to the ovaries occur are gastrointestinal tract (pylorus, colon and rarely small intestine), gallbladder, pancreas, breast and endometrial carcinoma.* These are usually bilateral tumors which maintain shape of the ovary. Histologically 'signet ring' looking cells are characteristic of Krukenberg tumor.* In most patients with Krukenberg's tumors, the prognosis is poor. Median survival being less than a year. Rarely, no primary site can be identified and the Krukenberg's tumor may be a primary tumor.Also know: Metastatic tumors from the GI tract can be associated with sex hormone (estrogen and androgen) production.Patient may present with postmenopausal bleeding.

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