Bilateral hilar lymphadenopathy with non-caseating granuloma is seen in -

Sarcoidosis Sarcoidosis is an immune system disorder characterized by the presence of non-caseating granulomas. The cause of the disease is still unknown. Virtually any organ can be affected, however, granulomas most often appear in the lung or the lymph nodes → Bilateral hilar lymphadenopathy or lung involvement is visible on chest radiograph in 90% of cases. Histology Histologically involved tissues show the classical non-caseating granulomas, composed of an aggregate of tightly clustered epithelioid cells, often with Langhans or foreign body type giant cells. Central necrosis is unusual → noncaseating. Granulomas also contain. i. Schaumann bodies → Laminated concretions composed of calcium and proteins. ii. Asteroid bodies  → Stellate inclusions within giant cells.