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Pediatrics Hemorrhagic and Thrombotic Diseases 802202d3

HSP doesn't cause -

A
Hemoptysis
B
Purpurae
C
Arthritis
D
Abdominal pain
High-Yield Explanation
Ans. is 'a' i.e., HemoptysisHenoch-Schonlein purpurao Henoch - Schonlein purpura is vasculitis of small vessels (capillaries, venule or arterioles) and characterized by deposition of IgA in the wall of involved vessels.o H.S. purpura is characterized by tetrad of purpura, arthritis, glomerulonephritis, and abdominal pain. Gross hematuria is seen in 20-30% of cases.o All changes result from the deposition of circulating immune complexes, containing IgA and complement on the endothelium of the blood vessels throughout the body and within the glomerular mesangial regionso Diagnosis is confirmed by presence of palpable purpura with normal platelet count along with one or more of the following : abdominal pain, arthralgia/arthritis and mesangial deposition of IgA.o Renal manifestations usually start at the onset or within 3 months of onset of other symptoms.

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