All statements about papillary thyroid cancer are true except:
High-Yield Explanation
Discussing options one by one: OPTION 1 - TRUE - Papillary thyroid cancer is most common subtype of thyroid cancer OPTION 2 - TRUE - Follicular variant of papillary cancer is most common type & is easily misdiagnosed as follicular ca. OPTION 3 - FALSE - RET-PTC gene mutation & radiation exposure are most impoant risk factors. OPTION 4 - TRUE - Its diagnosis is made by presence of nuclear finding like Orphan Annie eye nuclei, intranuclear inclusions ("pseudo-inclusions") ,intranuclear grooves & not on papillae formation.