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Pharmacology General 7ffa620c

A 5-year-old child is brought to the hospital with the complaint of fever, cough, breathlessness and chest pain. On examination he is found to be dull, but irritable with fast pulse (116/min), rapid breathing (RR 50/min) and indrawing of lower chest during inspiration, wheezing, crepitations and mild dehydration. Body temperature is 40°C (104°F). The paediatrician makes a provisional diagnosis of acute pneumonia and orders relevant haematological as well as bacteriological investigations. He decides to institute antibiotic therapy.In case he selects an antibiotic which can be given orally as well as by i.m. or i.v. injection,which route of administration will be most appropriate in this case?

A
Oral
B
i.m.
C
i.v.
D
s.c.
High-Yield Explanation
Since the child is seriously ill, a fast and more predictable action of the antibiotic is needed; a parenteral route of administration is appropriate. Moreover, oral dosing may be difficult in  this  case  as  the  child  is  dull  and  irritable.  Entering  a  vein  for  i.v.  injection  is  relatively difficult  in  children,  particularly  in  the  presence  of  dehydration.  Therefore,  the  antibiotic may  be  injected  i.m.  However, if  an i.v.  line  is  set  up  for  rehydration, the antibiotic may be administered  through  the  i.v.  line.

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