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Medicine General 7fbfe2bf

The genetic factors that can increase the susceptibility and modify the severity of pancreatic injury in acute pancreatitis are all, except:

A
Cationic trypsinogen mutations
B
Pancreatic secretory trypsin inhibitor
C
CFTR
D
ATP7a gene mutation
High-Yield Explanation
There are some genetic factors that can increase the susceptibility and/or modify the severity of pancreatic injury in acute pancreatitis. They are, (1) Cationic trypsinogen mutations (2) Pancreatic secretory trypsin inhibitor (SPINK1) (3) CFTR, and (4) Monocyte chemotactic protein (MCP-1) Menkes syndrome is caused by mutations in the ATP7A gene. Reference: Harrisons Principles of Internal Medicine, 18th Edition, Page 2636

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