Malformations of the following organ system of the fetus are found to be most commonly associated with Single umbilical aery .

Malformation of the genitourinary system is generally associated with the single umbilical aery. Paediatric complications associated with single umbilical aery include: An isolated SUA is associated with renal malformations in 7-9 per cent of infants. Vesicoureteric reflux (VUR) is the most common abnormality occurring in 4 per cent of infants with an isolated SUA. In a meta analysis of 26 studies the incidence of any renal abnormality associated with isolated SUA was 8 per cent, with only 4 per cent requiring treatment of the abnormality. From this meta analysis the investigation of 14 cases of isolated SUA would yield one patient requiring treatment. In another study VUR was also the most common abnormality requiring treatment and three out of five of their patients had a urinary tract infection (UTI) before the age of three months. Reference: GHAI Essential pediatrics, 8th edition